14 August 2026
Three Scientific Publications in Two Months by Our Research Assistant Nilgün Yıldız
Research Assistant Nilgün Yıldız from the Department of Physiotherapy and Rehabilitation contributed to three scientific articles published in June and July 2026 in the fields of pediatric rehabilitation, neurophysiology, and neuromuscular mechanisms. The studies provide scientific evidence on current research topics ranging from rehabilitation approaches in children with hemophilia to the regulation of spinal reflexes during mechanical and oscillatory loading.
Three Scientific Articles by Res. Asst. Nilgün Yıldız in June and July
Research Assistant Nilgün Yıldız from the Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences at Istanbul Gelisim University, contributed to three scientific articles published during June and July 2026. Covering topics ranging from rehabilitation in children with hemophilia to spinal reflex responses to mechanical loading and neurophysiological regulation during whole-body vibration, the studies bring together different research dimensions within physiotherapy and rehabilitation.
Effects of Rehabilitation Approaches on Children with Hemophilia: Systematic Review
The systematic review evaluated the effectiveness of physiotherapy and rehabilitation interventions used in children with hemophilia. Nine randomized controlled trials involving a total of 295 participants aged between 8 and 16 years were included. The findings indicated that laser therapy and therapeutic resistance exercise, when added to conventional physiotherapy, may contribute to improvements in pain, joint range of motion, muscle strength, and functional capacity. The authors also emphasized the need for further studies with stronger methodological quality to consolidate the available evidence and support clearer rehabilitation recommendations for the pediatric hemophilia population.
Loading modulates monosynaptic transmission from spindle primary afferents to motoneurons in humans
This study investigated how different levels of mechanical loading influence the soleus H-reflex in healthy adults. Participants were assessed under graded loading conditions corresponding to different percentages of body weight. H-reflex amplitude progressively decreased as mechanical load increased, whereas background electromyographic activity showed an opposite pattern. This divergence indicates that spinal reflex excitability does not simply increase in parallel with muscle activation. The findings therefore provide further evidence that neural control mechanisms dynamically regulate spinal reflex responses according to changing postural and mechanical demands.
Load-dependent dissociation between H-reflex amplitude and background EMG activity during oscillatory loading: implications for the bone myoregulation reflex
The third article examined the relationship between H-reflex excitability and motor output during whole-body vibration and oscillatory mechanical loading. In healthy volunteers, increasing oscillatory load was associated with reduced H-reflex responses together with increased background muscle activity. The study also identified an association between bone myoregulation reflex activity and motor output. These findings provide a potential mechanistic framework for understanding neuromuscular responses to load-dependent oscillatory stimulation and contribute to ongoing research into the interaction between mechanical loading, spinal reflex pathways, and neuromuscular control.
From Clinical Rehabilitation to Neurophysiology
Taken together, the three publications share a common interest in movement, mechanical loading, rehabilitation, and the physiological mechanisms that support human function. While the systematic review evaluates clinically relevant rehabilitation approaches through the available scientific evidence, the two neurophysiological studies investigate how spinal and neuromuscular responses are modulated during different forms of mechanical loading.
In this respect, clinical rehabilitation questions and experimental neurophysiology are brought together within the same period of scientific productivity. The contribution of Research Assistant Nilgün Yıldız to three publications within two months is also notable for its breadth across pediatric rehabilitation, neurophysiology, postural control, and neuromuscular mechanisms.
The use of different research populations, methodologies, and study designs may contribute to the development of evidence-based practice, a deeper understanding of the neurophysiological foundations of rehabilitation, and the formulation of future research questions. The studies also demonstrate how research ranging from systematic evidence synthesis to experimental human neurophysiology can contribute to a broader understanding of movement and rehabilitation sciences.
Detailed information about the publications can be accessed through the links below, while additional information regarding the researcher's academic publications and scientific activities is available through her AVESIS profile.